By George Morstyn (auth.), Graham Molineux, MaryAnn Foote, Tara Arvedson (eds.)
Granulocyte colony-stimulating issue (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. improvement of recombinant human G-CSF has had a profound effect at the remedy of many ailments, together with critical power neutropenia and melanoma, and has enabled peripheral stem phone transplantation to supplant bone marrow transplantation within the autologous atmosphere.
This Milestones in Drug Therapy quantity describes the adventure of the final twenty years of therapy with recombinant human G-CSF, together with the elemental technology, using recombinant human G-CSF in either the oncology and nononcology settings, and the protection and economics of its use. a few of the authors have been the unique investigators of recombinant human G-CSF and different authors are key researchers who offer their outlook for the following twenty years to be used of and learn with recombinant human G-CSF.
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