By S. J. Meltzer (auth.), Prof. Dr. med. Ernst-D. Kreuser, Prof. Dr. med. P. M. Schlag (eds.)
This quantity specializes in new and interesting techniques within the molecular and medical administration of gastrointestinal tumors. the 1st half provides contemporary insights into carcinogenesis, together with adjustments in cyclins and adhesion receptors, molecular constructions that may be new ambitions of gene remedy. the second one a part of the quantity bargains new diagnostic instruments, comparable to receptors for gastrointestinal hormones, proliferation markers, tumor suppressor proteins, and the a number of drug resistance gene, predicting reaction to remedy and analysis in gastrointestinal tumors. The 3rd half provides an replace of winning ways in basic and secondary prevention of colorectal carcinoma. dietary elements and pharmacologic brokers can essentially lessen the danger, and fecal occult blood exams and endoscopy can decrease the mortality in colorectal carcinoma. Laparoscopic staging with next biopsy of suspicious lymph nodes presents crucial details in esophageal and gastric melanoma. In in the community complicated gastric melanoma, preoperative chemotherapy presents adequate facts to enquire this strategy in comparison to fundamental surgical procedure. criteria have lately been proven within the adjuvant therapy of sufferers with gastrointestinal carcinoma, and promising new medicines, together with monoclonal antibodies, thymidylate synthase, and topoisomerase inhibitors, in addition to taxoids, are presently being proven in part I, II, and III trials of gastrointestinal tumors.
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